АПИКСАБАН В ЛЕЧЕНИИ ФИБРИЛЛЯЦИИ ПРЕДСЕРДИЙ: РАНДОМИЗИРОВАННЫЕ ИССЛЕДОВАНИЯ И ПОВСЕДНЕВНАЯ КЛИНИЧЕСКАЯ ПРАКТИКА
https://doi.org/10.21518/2307-1109-2017-1-67-77
Аннотация
Апиксабан является единственным НОАК, применение которого ассоциируется со снижением частоты как инсультов, так и больших кровотечений. Соответственно, апиксабан является препаратом выбора у пациентов с неклапанной ФП, в т. ч. у пожилых пациентов, больных с высоким риском геморрагических осложнений, а также у пациентов с нарушенной почечной функцией. В реальной клинической практике показатели эффективности и безопасности применения апиксабана не уступают таковым, полученным в исследовании ARISTOTLE. Апиксабан безопасен при использовании во время кардиоверсии и катетерной абляции. Результаты доклинического исследования дают основание для дальнейшего изучения возможности применения апиксабана у пациентов с «клапанной» ФП.
Об авторах
О. О. Шахматова
НИИ кардиологии им. А.Л. Мясникова РКНПК МЗ РФ
Россия
к.м.н.
Россия
к.м.н.
Е. П. Панченко
НИИ кардиологии им. А.Л. Мясникова РКНПК МЗ РФ
Россия
д.м.н., профессор
Россия
д.м.н., профессор
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Рецензия
Для цитирования:
Шахматова О.О., Панченко Е.П. АПИКСАБАН В ЛЕЧЕНИИ ФИБРИЛЛЯЦИИ ПРЕДСЕРДИЙ: РАНДОМИЗИРОВАННЫЕ ИССЛЕДОВАНИЯ И ПОВСЕДНЕВНАЯ КЛИНИЧЕСКАЯ ПРАКТИКА. Атеротромбоз. 2017;(1):67-77. https://doi.org/10.21518/2307-1109-2017-1-67-77
For citation:
Shakhmatova O.O., Panchenko E.P. APIXABAN IN THE TREATMENT OF ATRIAL FIBRILLATION: RANDOMIZED TRIALS AND EVERYDAY CLINICAL PRACTICE. Aterotromboz = Atherothrombosis. 2017;(1):67-77. (In Russ.) https://doi.org/10.21518/2307-1109-2017-1-67-77
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