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Risk assessment and prevention of venous thromboembolism among hospitalized patients: Results of the regional multicenter study

https://doi.org/10.21518/2307-1109-2021-11-1-26-40

Abstract

Introduction. Venous thromboembolism (VTE) is a major public health issue that is frequently underestimated. The primary objective of this multicenter study was to identify patients at risk for VTE, and to define the rate of patients receiving appropriate prophylaxis in the regions of Kazakhstan.

Materials and methods. Standardized case report forms were filled by trained medical doctors on one predefined day in selected hospitals. Data were analyzed by independent biostatistician. Risk of VTE was categorized according to Caprini score which was recommended by 2004 American College of Chest Physicians (ACCP) guidelines.

Results. 432 patients from 4 regions of Kazakhstan; 169 (39.10%) medical patients and 263 (60.9%) surgical patients were eligible for the study. Patients were at low (10%), moderate (19.2%), high (33.6%) and very high risk (37.3%) for VTE. The main risk factors (RF) of VTE among hospitalized patients were heart failure (HF), obesity, prolonged bed rest, and the presence of acute non-infective inflammation. From total number of hospitalized patients with RF with indications to VTE prophylaxis, 58.1% of patients received pharmacological prophylaxis and only 24.6% of them received VTE prophylaxis according ACCP. On the other hand, 23.5% patients with the risk of VTE but who were not eligible for it received pharmacological prophylaxis.

Conclusion. These results indicate the existence of inconsistency between eligibility for VTE prophylaxis on one hand and its application in practice (p < 0.001). Risk factors for VTE and eligibility for VTE prophylaxis are common, but VTE prophylaxis and guidelines application are low.

About the Authors

A. B. Sugraliyev
Asfendiyarov Kazakh National Medical University; Almaty Central Clinical Hospital
Kazakhstan

Akhmetzhan B. Sugraliyev, Cand. Sci. (Med.), Head of Department of Internal Diseases, Asfendiyarov Kazakh National Medical University; Doctor Consultant of Almaty Central Clinical Hospital

94, Tole bi St., Almaty, 050000,

139, Panfilov St., Almaty, 050000



Sh. S. Aktayeva
Almaty Central Clinical Hospital
Kazakhstan

Shynar S. Aktayeva, Cardiologist of Intensive Care Unit

139, Panfilov St., Almaty, 050000



Sh. B. Zhangelova
Asfendiyarov Kazakh National Medical University
Kazakhstan

Sholpan B. Zhangelova, Cand. Sci. (Med.), Professor of the Department of Internal Diseases with a Course of Propaedeutics

94, Tole bi St., Almaty, 050000



S. A. Shiller
Almaty Central Clinical Hospital
Kazakhstan

Sergey A. Shiller, Master of Health, Master of Economics and Business, Vice President

139, Panfilov St., Almaty, 050000



Zh. M. Kussymzhanova
Almaty Central Clinical Hospital
Kazakhstan

Zhanara M. Kussymzhanova, Cand. Sci. (Med.), Head of Cardiology Department

139, Panfilov St., Almaty, 050000



S. K. Tuganbekova
National Scientific Medical Center
Kazakhstan

Saltanat K. Tuganbekova, Dr. Sci. (Med.), Head of the Department of Internal Diseases

42, Abylai Khan Ave., Nur-Sultan, 010000



Zh. S. Sheriyazdan
Almaty City Hospital №7
Kazakhstan

Zhadyra S. Sheriyazdan, Deputy Chief Physician

20, Kalkaman microdistrict, Almaty, 050006



B. L. Danyarova
Karaganda Regional Clinical Hospital
Kazakhstan

Bayan L. Danyarova, Deputy Director of Strategic Development

15, Erubaev St., Karaganda, 100000



V. E. Tsai
Chimkent Regional Clinical Hospital
Kazakhstan

Viacheslav E. Tsai, Head of Intensive Care Unit

4, Maily-Koja St., Shimkent, 160011



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For citations:


Sugraliyev A.B., Aktayeva Sh.S., Zhangelova Sh.B., Shiller S.A., Kussymzhanova Zh.M., Tuganbekova S.K., Sheriyazdan Zh.S., Danyarova B.L., Tsai V.E. Risk assessment and prevention of venous thromboembolism among hospitalized patients: Results of the regional multicenter study. Aterotromboz = Atherothrombosis. 2021;(1):26-40. (In Russ.) https://doi.org/10.21518/2307-1109-2021-11-1-26-40

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