DABIGATRAN AND IDARUZIZUMAB. NEW OPPORTUNITIES FOR IMPROVING PATIENT SAFETY
https://doi.org/10.21518/2307-1109-2019-1-53-61
Abstract
The widespread use of new oral anticoagulants in clinical practice requires improving the safety of medication use, i.e. the use of specific reversal agents, if necessary. Idarucizumab, a humanied monoclonal antibody fragment, is the first reversal agent authorized in our country that binds to dabigatran. Its efficacy and safety have been validated in several clinical trials, and its use gains experience in real clinical practice.
About the Authors
N. A. Novikova
Federal State Autonomous Educational Institution of Higher Education First Moscow State Medical University named after I.M. Sechenov of the Ministry of Health (Sechenov University)
Russian Federation
Russian Federation
Dr. of Sci. (Med.), Professor of Chair for Emergency and Preventive Cardiology
8, Trubetskaya Street, Moscow, 119991, Russia, p. 2
A. N. Volovchenko
Federal State Autonomous Educational Institution of Higher Education First Moscow State Medical University named after I.M. Sechenov of the Ministry of Health (Sechenov University)
Russian Federation
Russian Federation
a physician of Resuscitation and Intensive Care Unit No 1, University Clinical Hospital No 1
8, Trubetskaya Street, Moscow, 119991, Russia, p. 2
D. A. Parfenov
Federal State Autonomous Educational Institution of Higher Education First Moscow State Medical University named after I.M. Sechenov of the Ministry of Health (Sechenov University)
Russian Federation
Russian Federation
Head of Resuscitation and Intensive Care Unit No 1, University Clinical Hospital No 1
8, Trubetskaya Street, Moscow, 119991, Russia, p. 2
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Review
For citations:
Novikova N.A., Volovchenko A.N., Parfenov D.A. DABIGATRAN AND IDARUZIZUMAB. NEW OPPORTUNITIES FOR IMPROVING PATIENT SAFETY. Aterotromboz = Atherothrombosis. 2019;(1):53-61. (In Russ.) https://doi.org/10.21518/2307-1109-2019-1-53-61
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